Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246845 | 0.86 | POLB (0.38) | MAOATSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7247092 | 0.83 | TSHR (0.40) | MAOATSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL7700461 | 0.78 | PLA2G4A (0.47) | MAOAPPARGPLA2G4ASMN1; SMN2 | |
| SCHEMBL18733285 | 0.71 | PLA2G4A (0.58) | MAOAPLA2G4A | |
| SCHEMBL7247632 | 0.70 | SRD5A2 (0.40) | SMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL6514090 | 0.70 | MAOA (0.47) | MAOAPLA2G4ANPC1LMNARAB9A | |
| SCHEMBL16894501 | 0.70 | MAOA (0.59) | MAOAPLA2G4ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL18733283 | 0.69 | PLA2G4A (0.47) | MAOAPLA2G4ATSHRHSD17B10 | |
| SCHEMBL1553259 | 0.68 | SRD5A2 (0.58) | MAOAPPARGNPC1LMNARAB9A | |
| SCHEMBL92665 | 0.67 | KMT2A (0.47) | MAOAMAPK1SMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000620-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-01-03 | — | — | WO | disclosed |