Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 7/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246843 | 0.86 | KDM4E (0.41) | PLA2G4AMAOAKDM4ECRHBPCRHR2 | |
| SCHEMBL7247084 | 0.83 | KDM4E (0.47) | KDM4ECRHBPCRHR2SMN1; SMN2NOD2 | |
| SCHEMBL7700463 | 0.78 | MAOA (0.40) | PLA2G4AMAOASMN1; SMN2PPARG | |
| SCHEMBL18733285 | 0.77 | PLA2G4A (0.58) | PLA2G4AMAOAKDM4ENOD2NOD1 | |
| SCHEMBL7252148 | 0.76 | MCL1 (0.38) | MAOAKDM4ECRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL25505995 | 0.75 | HSD17B10 (0.47) | MAOAKDM4ECRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL30041116 | 0.75 | HSD17B10 (0.47) | MAOAKDM4ECRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL18733283 | 0.73 | PLA2G4A (0.47) | PLA2G4AMAOAKDM4ENOD2NOD1 | |
| SCHEMBL18733230 | 0.72 | MAOA (0.51) | PLA2G4AMAOA | |
| SCHEMBL16894501 | 0.72 | MAOA (0.59) | PLA2G4AMAOAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000620-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-01-03 | — | — | WO | disclosed |