Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700589 | 1.00 | SLC6A9 (0.62) | SLC6A9MTNR1BMTNR1AHTR6KDM4E | |
| SCHEMBL7704407 | 0.88 | SLC6A9 (0.60) | SLC6A9MTNR1BMTNR1AKDM4EALDH1A1 | |
| SCHEMBL7700569 | 0.87 | SLC6A9 (0.81) | SLC6A9MTNR1BMTNR1ALTA4H | |
| SCHEMBL7700515 | 0.86 | SLC6A9 (0.49) | SLC6A9TACR1 | |
| Lithium Ion SCHEMBL7703444 | 0.85 | SLC6A9 (0.62) | SLC6A9MTNR1BMTNR1AHTR6TACR1 | |
| SCHEMBL7700190 | 0.84 | SLC6A9 (0.65) | SLC6A9MAPTLTA4H | |
| SCHEMBL7704263 | 0.83 | SLC6A9 (0.55) | SLC6A9MTNR1BMTNR1AALDH1A1 | |
| SCHEMBL7698449 | 0.79 | SLC6A9 (0.62) | SLC6A9MTNR1BMTNR1AHTR6TACR1 | |
| SCHEMBL1761217 | 0.79 | SLC6A9 (0.74) | SLC6A9MTNR1BMTNR1ATACR1SIGMAR1 | |
| SCHEMBL7709405 | 0.79 | SLC6A9 (0.74) | SLC6A9MTNR1BMTNR1ATACR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |