Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700589 | 0.88 | SLC6A9 (0.62) | SLC6A9MTNR1AMTNR1BSIGMAR1ALDH1A1 | |
| SCHEMBL7700588 | 0.88 | SLC6A9 (0.62) | SLC6A9MTNR1AMTNR1BSIGMAR1ALDH1A1 | |
| SCHEMBL12591535 | 0.87 | SLC6A9 (0.71) | SLC6A9MTNR1AMTNR1BSIGMAR1ALDH1A1 | |
| SCHEMBL7700569 | 0.87 | SLC6A9 (0.81) | SLC6A9MTNR1AMTNR1BLTA4H | |
| Hydrochloric Acid SCHEMBL7706074 | 0.86 | SLC6A9 (0.70) | SLC6A9MTNR1AMTNR1BSIGMAR1ALDH1A1 | |
| SCHEMBL7700190 | 0.84 | SLC6A9 (0.65) | SLC6A9MAPTLTA4HFFAR1 | |
| SCHEMBL7704263 | 0.82 | SLC6A9 (0.55) | SLC6A9MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL19501073 | 0.81 | SIGMAR1 (0.58) | SLC6A9MTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL1761264 | 0.78 | SLC6A9 (0.81) | SLC6A9MTNR1AMTNR1B | |
| SCHEMBL7709405 | 0.77 | SLC6A9 (0.74) | SLC6A9MTNR1AMTNR1BSIGMAR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |