Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.49 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 6/20 | 0.38 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698703 | 0.88 | SLC6A9 (0.59) | SLC6A9FFAR1TACR1PPARDPPARA | |
| SCHEMBL7700589 | 0.86 | SLC6A9 (0.62) | SLC6A9TACR1 | |
| Lithium Ion SCHEMBL7702956 | 0.86 | SLC6A9 (0.49) | SLC6A9FFAR1RORCTACR1SRD5A1 | |
| SCHEMBL7700588 | 0.86 | SLC6A9 (0.62) | SLC6A9TACR1 | |
| SCHEMBL1761236 | 0.80 | SLC6A9 (0.70) | SLC6A9FFAR1TACR1PPARDPPARA | |
| SCHEMBL7700569 | 0.77 | SLC6A9 (0.81) | SLC6A9PPARD | |
| SCHEMBL7704407 | 0.77 | SLC6A9 (0.60) | SLC6A9FFAR1TACR1 | |
| Lithium Ion SCHEMBL7702768 | 0.77 | SLC6A9 (0.60) | SLC6A9FFAR1TACR1PPARDPPARA | |
| Lithium Ion SCHEMBL7698371 | 0.76 | SLC6A9 (0.53) | SLC6A9SRD5A1 | |
| Lithium Ion SCHEMBL7705019 | 0.76 | SLC6A9 (0.56) | SLC6A9PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |