Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703205 | 0.95 | NPC1 (0.51) | NPC1RAB9AALDH1A1TP53PKM | |
| SCHEMBL7698678 | 0.84 | MAPK1 (0.54) | NPC1RAB9AALDH1A1TP53MAPK1 | |
| SCHEMBL7698117 | 0.83 | NPC1 (0.57) | NPC1RAB9AALDH1A1TP53PKM | |
| SCHEMBL7693531 | 0.83 | KCNQ3 (0.43) | NPC1RAB9AALDH1A1TP53MAPK1 | |
| SCHEMBL7698274 | 0.82 | RAB9A (0.51) | NPC1RAB9ATP53PKMMAPK1 | |
| SCHEMBL7700032 | 0.82 | NPC1 (0.55) | NPC1RAB9AALDH1A1TP53MEN1 | |
| SCHEMBL7699494 | 0.82 | NPC1 (0.58) | NPC1RAB9AALDH1A1TP53MEN1 | |
| SCHEMBL7705439 | 0.82 | KDM4E (0.50) | NPC1RAB9AALDH1A1TP53MEN1 | |
| SCHEMBL7704827 | 0.82 | NPC1 (0.55) | NPC1RAB9AALDH1A1TP53MEN1 | |
| SCHEMBL7699717 | 0.81 | HPGD (0.54) | NPC1RAB9AALDH1A1TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |