Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700629 | 0.95 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7695853 | 0.85 | HPGD (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7693531 | 0.84 | KCNQ3 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7698117 | 0.81 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7698274 | 0.80 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2POLBTSHR | |
| SCHEMBL7698678 | 0.80 | MAPK1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7699494 | 0.79 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7704827 | 0.79 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7705439 | 0.79 | KDM4E (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7700032 | 0.79 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |