Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698887 | 0.86 | ALDH1A1 (0.49) | KCNQ3KCNQ2KMT2AALDH1A1MAPK1 | |
| SCHEMBL7699494 | 0.86 | NPC1 (0.58) | KMT2AALDH1A1NPC1RAB9AHDAC3 | |
| SCHEMBL7701371 | 0.85 | GAA (0.48) | KMT2AALDH1A1MAPK1HTTNPC1 | |
| SCHEMBL7703205 | 0.84 | NPC1 (0.51) | KMT2AALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL7700629 | 0.83 | NPC1 (0.48) | KMT2AALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL7695399 | 0.81 | KDM4E (0.51) | KMT2AALDH1A1MAPK1HTTNPC1 | |
| SCHEMBL7699717 | 0.81 | HPGD (0.54) | KMT2AALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL7698147 | 0.79 | NCOA1 (0.42) | KMT2AALDH1A1MAPK1HTTNPSR1 | |
| SCHEMBL7698117 | 0.78 | NPC1 (0.57) | KMT2AALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL7701316 | 0.78 | DGAT1 (0.49) | KMT2AALDH1A1HTTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |