SCHEMBL7700697

SCHEMBL7700697

CCO[Si](OCC)(c1ccccc1)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.33
TP53 P04637 2/20 0.32
ACHE P22303 1/20 0.32
RELA Q04206 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647380 0.89 LTA4H (0.37) LTA4HTP53ACHERELANPSR1
SCHEMBL7697439 0.83 LMNA (0.36) LTA4HTP53ALDH1A1HPGDSMN1; SMN2
SCHEMBL645295 0.83 LTA4H (0.33) LTA4HTP53ACHERELANPSR1
SCHEMBL645248 0.83 LTA4H (0.33) LTA4HTP53ACHERELANPSR1
SCHEMBL9697358 0.81 TSHR (0.33) LTA4HTP53ACHETSHR
SCHEMBL7803280 0.81 TSHR (0.33) LTA4HTP53ACHETSHR
SCHEMBL7695586 0.80 LTA4H (0.43) LTA4HALDH1A1HPGDTSHR
SCHEMBL645564 0.77 LTA4H (0.38) LTA4HTP53RELANPSR1ESR1
SCHEMBL29900 0.75 LTA4H (0.37) LTA4HTP53RELANPSR1ESR1
SCHEMBL238216 0.75 DUT (0.38) LTA4HTP53ACHERELANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6344579-B1 REACTION OF FLUOROSILICON COMPOUND WITH REACTION OF SILICON WITH HYDROXY, ALKOXY OR ARYLOXY GROUP WITH DIFLUORODIAMINO COMPOUND MITSUI CHEMICALS, INC. (JP) 2002-02-05 US disclosed
EP-1138633-A1 PROCESS FOR PRODUCING FLUORINATED SILICON COMPOUND Mitsui Chemicals, Inc. (JP) 2001-10-04 EP disclosed