SCHEMBL7702076

SCHEMBL7702076

CS(=O)(=O)c1cccc2c1OCCC(C(=O)N=C(N)N)=C2

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 4/20 0.38
SLC9A2 Q9UBY0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6135636 0.99 SLC9A1 (0.37) SLC9A1SLC9A2
Hydrochloric Acid SCHEMBL6134781 0.99 SLC9A1 (0.37) SLC9A1SLC9A2
SCHEMBL7700710 0.87 KMT2A (0.31)
SCHEMBL7378220 0.83 FABP4 (0.35) SLC9A1
SCHEMBL6756789 0.83 KMT2A (0.33)
SCHEMBL7700742 0.81 PARP1 (0.36) SLC9A1SLC9A2
SCHEMBL7700277 0.81 SLC9A1 (0.34) SLC9A1SLC9A2
Hydrochloric Acid SCHEMBL7700819 0.81 PARP1 (0.38) SLC9A1SLC9A2
SCHEMBL7383369 0.81 SLC9A1 (0.39) SLC9A1SLC9A2
SCHEMBL7381905 0.80 SLC9A1 (0.44) SLC9A1SLC9A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6346527-B1 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-02-12 US claimed
EP-1073650-A1 GUANIDINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-02-07 EP claimed
WO-1999055690-A1 GUANIDINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-04 WO claimed
EP-1073650-A1 GUANIDINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-02-07 EP disclosed
WO-1999055690-A1 GUANIDINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-04 WO disclosed