Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967372 | 0.85 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL4632039 | 0.77 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL8501423 | 0.74 | EDNRA (0.77) | EDNRAEDNRB | |
| SCHEMBL7252302 | 0.74 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL5208967 | 0.71 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6789530 | 0.70 | STS (0.49) | — | |
| SCHEMBL7964834 | 0.69 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL6383356 | 0.65 | SLC6A3 (0.43) | — | |
| SCHEMBL27527148 | 0.65 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL4632053 | 0.65 | EDNRA (0.89) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342610-B2 | COMPOUNDS SUCH AS N-(4-BROMO-3-METHYL-5-ISOXAZOLYL)-2-N-BENZYLBENZO(B)THIOPHENE-3-SUFONAMIDE ADMINISTERED AS ENDOTHELIN PEPTIDE RECEPTOR ANTAGONISTS | TEXAS BIOTECHNOLOGY CORP. | 2002-01-29 | — | — | US | disclosed |