Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ARHGDIA | P52565 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221508 | 0.88 | OPRL1 (0.43) | OPRL1ALDH1A1HSD17B10KCNH2OPRK1 | |
| SCHEMBL7685312 | 0.83 | OPRL1 (0.39) | OPRL1ALDH1A1HSD17B10KCNH2OPRK1 | |
| SCHEMBL7697916 | 0.83 | OPRL1 (0.40) | OPRL1ALDH1A1KCNH2TACR1SLC6A4 | |
| SCHEMBL7222128 | 0.83 | ALDH1A1 (0.53) | OPRL1ALDH1A1HSD17B10KCNH2OPRK1 | |
| SCHEMBL7696516 | 0.82 | OPRK1 (0.43) | OPRL1ALDH1A1HSD17B10KCNH2OPRK1 | |
| SCHEMBL3157716 | 0.82 | OPRL1 (0.55) | OPRL1ALDH1A1HSD17B10OPRM1CHRM2 | |
| SCHEMBL16554606 | 0.81 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL16565769 | 0.81 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL16565906 | 0.81 | OPRL1 (0.31) | OPRL1 | |
| SCHEMBL16554204 | 0.81 | OPRL1 (0.31) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057262-A2 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |