Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 5/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221508 | 0.83 | OPRL1 (0.43) | OPRK1KCNH2OPRL1ALDH1A1HSD17B10 | |
| SCHEMBL7221029 | 0.83 | CHRNB2 (0.36) | OPRL1CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7700183 | 0.82 | CHRNB2 (0.33) | OPRL1CHRNB2CHRNB4CHRNA3JAK2 | |
| SCHEMBL7700751 | 0.82 | OPRL1 (0.40) | OPRK1KCNH2OPRL1ALDH1A1HSD17B10 | |
| SCHEMBL7699063 | 0.79 | CHRNB2 (0.34) | OPRL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7685312 | 0.79 | OPRL1 (0.39) | OPRK1KCNH2OPRL1ALDH1A1HSD17B10 | |
| SCHEMBL7222128 | 0.79 | ALDH1A1 (0.53) | OPRK1KCNH2OPRL1ALDH1A1HSD17B10 | |
| SCHEMBL5476783 | 0.78 | KMT2A (0.51) | OPRK1KCNH2OPRL1ALDH1A1OPRM1 | |
| SCHEMBL3157716 | 0.78 | OPRL1 (0.55) | OPRL1ALDH1A1HSD17B10OPRM1 | |
| SCHEMBL7697700 | 0.78 | GRM5 (0.41) | RETCHRNB2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057263-A1 | 8-AZABICYCLO \"3.2.1.! OCTANES AS INSECTICIDES | SYNGENTA LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |