Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651471 | 1.00 | ACLY (0.32) | ACLYFAAHTRPV1 | |
| SCHEMBL6651466 | 1.00 | ACLY (0.32) | ACLYFAAHTRPV1 | |
| SCHEMBL14489225 | 0.83 | FAAH (0.33) | ACLYFAAHTRPV1 | |
| SCHEMBL7697578 | 0.83 | FAAH (0.35) | ACLYFAAHTRPV1 | |
| SCHEMBL7697580 | 0.83 | FAAH (0.35) | ACLYFAAHTRPV1 | |
| SCHEMBL7701604 | 0.80 | — | — | |
| SCHEMBL7698667 | 0.78 | — | — | |
| SCHEMBL7698672 | 0.78 | — | — | |
| SCHEMBL7701671 | 0.78 | — | — | |
| SCHEMBL6651139 | 0.75 | MLYCD (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056716-B1 | CYCLOHEXANEDIOLE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| US-6184422-B1 | TREATMENT AND PREVENTION OF HYPERPROLIFERATIVE SKIN DISEASES; REVERSING CONDITIONS ASSOCIATED WITH PHOTODAMAGE; ANTITUMOR, -CARCINOGENIC AGENTS; PSORIASIS; DISORDERS OF NEOPLASTIC DISEASES; KERATINIZATION/KERATOSIS; ACNE; SEBORRHEA | HOFFMAN-LA ROCHE INC. | 2001-02-06 | — | — | US | disclosed |