Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695101 | 0.93 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7698845 | 0.91 | KDM4E (0.53) | ALDH1A1TSHRNPC1RAB9AKDM4E | |
| SCHEMBL7663107 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TSHRNPC1RAB9ATDP1 | |
| SCHEMBL7699705 | 0.83 | C1R (0.43) | ALDH1A1TSHRL3MBTL1MAPK1NPSR1 | |
| SCHEMBL7695229 | 0.79 | KDM4E (0.56) | ALDH1A1TSHRNPC1RAB9AKDM4E | |
| SCHEMBL7695264 | 0.76 | MEN1 (0.50) | ALDH1A1TSHRNPC1TDP1KDM4E | |
| SCHEMBL7697083 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1KDM4EHTT | |
| SCHEMBL7700594 | 0.76 | C1R (0.44) | ALDH1A1TSHRL3MBTL1MAPK1NPSR1 | |
| SCHEMBL7700431 | 0.75 | TP53 (0.47) | ALDH1A1TSHRKDM4EHTTMAPK1 | |
| SCHEMBL7667933 | 0.74 | ALDH1A1 (0.67) | ALDH1A1TSHRNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |