SCHEMBL7699705

SCHEMBL7699705

NCCCc1oc(-c2ccccc2C(F)(F)F)nc1S(=O)(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
C1R P00736 1/20 0.43
TP53 P04637 4/20 0.41
ALDH1A1 P00352 4/20 0.39
TSHR P16473 3/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 1/20 0.38
NOTUM Q6P988 2/20 0.38
PSMB8 P28062 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
PLA2G1B P04054 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
HSD17B10 Q99714 2/20 0.36
MAPK1 P28482 1/20 0.36
HTR6 P50406 1/20 0.36
MEN1 O00255 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7700594 0.93 C1R (0.44) C1RTP53ALDH1A1TSHRKMT2A
SCHEMBL7701107 0.89 C1R (0.46) C1RTP53ALDH1A1TSHRKMT2A
SCHEMBL7700943 0.83 ALDH1A1 (0.44) TP53ALDH1A1TSHRKMT2AGAA
SCHEMBL7695101 0.76 ALDH1A1 (0.46) TP53ALDH1A1TSHRKMT2AGAA
SCHEMBL7698845 0.75 KDM4E (0.53) TP53ALDH1A1TSHRKMT2AGAA
SCHEMBL7701108 0.75 KMT2A (0.62) C1RTP53ALDH1A1TSHRKMT2A
SCHEMBL7700596 0.75 L3MBTL1 (0.53) TP53ALDH1A1KMT2AGAAL3MBTL1
SCHEMBL7697083 0.74 ALDH1A1 (0.55) TP53ALDH1A1TSHRKMT2AMAPT
SCHEMBL7699708 0.73 L3MBTL1 (0.56) ALDH1A1KMT2AGAAL3MBTL1MAPT
SCHEMBL7700470 0.72 KMT2A (0.44) C1RTP53ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002100842-A1 SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS MERCK PATENT GMBH (DE) 2002-12-19 WO disclosed