Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350216 | 0.82 | CA2 (0.41) | CA2CES2CES1 | |
| SCHEMBL7700023 | 0.76 | CA1 (0.33) | CA1CA2CA12CA14ALOX15 | |
| SCHEMBL22444372 | 0.74 | FFAR3 (0.36) | CA1CA2CA12CA14ALOX15 | |
| SCHEMBL585350 | 0.71 | CA1 (0.33) | CA1ALOX15LMNABLMPMP22 | |
| SCHEMBL11513667 | 0.67 | ALOX15 (0.30) | ALOX15 | |
| SCHEMBL27564171 | 0.67 | BLM (0.33) | CA1CA2ALOX15LMNABLM | |
| SCHEMBL4573542 | 0.65 | CA1 (0.31) | CA1CA2 | |
| Butane SCHEMBL147084 | 0.64 | — | — | |
| Urea SCHEMBL28190948 | 0.63 | TDP1 (0.43) | CA1CA2ALOX15CES2CES1 | |
| Propane SCHEMBL27521159 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002070507-A2 | GLYCORTICOID RECEPTOR ANTAGONISTS FOR TREATMENT OF DIABETES | ABBOTT LABORATORIES (US) | 2002-09-12 | — | — | WO | claimed |