Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681972 | 0.86 | LMNA (0.47) | LMNATSHRNPC1RAB9AALPI | |
| SCHEMBL9028692 | 0.85 | ALDH1A1 (0.52) | LMNATSHRNPC1RAB9AALPI | |
| SCHEMBL5617244 | 0.85 | ALDH1A1 (0.52) | LMNATSHRNPC1RAB9AALPI | |
| SCHEMBL3505882 | 0.85 | ALDH1A1 (0.52) | LMNATSHRNPC1RAB9AALPI | |
| SCHEMBL1838248 | 0.82 | SLC6A2 (0.54) | TSHRNPC1RAB9AALPIPKM | |
| SCHEMBL6826673 | 0.82 | TSHR (0.53) | LMNATSHRNPC1RAB9AALPI | |
| SCHEMBL28914994 | 0.79 | SLC6A2 (0.50) | TSHRNPC1RAB9AALPIPKM | |
| SCHEMBL10658684 | 0.79 | NPC1 (0.55) | LMNATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL28237997 | 0.79 | SLC6A2 (0.50) | TSHRNPC1RAB9AALPIPKM | |
| SCHEMBL1811694 | 0.79 | SLC6A2 (0.50) | TSHRNPC1RAB9AALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348620-B1 | FORMING DESIRED HYDROGENATED DERIVATIVES WITH GOOD TO VERY GOOD YIELDS AND EXCESSES OF ENANTIOMERS | DEGUSSA-HULS AG (DE) | 2002-02-19 | — | — | US | disclosed |