Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703221 | 0.87 | RAB9A (0.67) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL7701405 | 0.85 | NPC1 (0.56) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL7699717 | 0.85 | HPGD (0.54) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL7699800 | 0.85 | RAB9A (0.67) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL7698683 | 0.84 | MAPT (0.52) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL7694301 | 0.84 | RAB9A (0.52) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL7697078 | 0.83 | HPGD (0.56) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL7693588 | 0.83 | KDM4E (0.65) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL7700048 | 0.83 | NPC1 (0.50) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL7699389 | 0.83 | NPC1 (0.54) | ALDH1A1HPGDRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |