Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | HPGD | P15428 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697078 | 0.93 | HPGD (0.56) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL7700048 | 0.91 | NPC1 (0.50) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL7703221 | 0.91 | RAB9A (0.67) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL7698680 | 0.87 | MAPT (0.53) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL7698683 | 0.85 | MAPT (0.52) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL7694301 | 0.85 | RAB9A (0.52) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL7701153 | 0.85 | ALDH1A1 (0.63) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL7699494 | 0.85 | NPC1 (0.58) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL7693588 | 0.84 | KDM4E (0.65) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL7698887 | 0.83 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |