Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CEPT1 | Q9Y6K0 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705248 | 0.88 | CETP (0.59) | MAPTHPGDCYP2C19NPC1RAB9A | |
| SCHEMBL7703221 | 0.87 | RAB9A (0.67) | MAPTHPGDCYP2C19NPC1RAB9A | |
| SCHEMBL7701405 | 0.85 | NPC1 (0.56) | MAPTHPGDHTTNPC1RAB9A | |
| SCHEMBL7695399 | 0.85 | KDM4E (0.51) | MAPTHPGDCYP2C19ALOX12MAPK1 | |
| SCHEMBL7694301 | 0.84 | RAB9A (0.52) | MAPTHPGDCYP2C19HTTNPC1 | |
| SCHEMBL7701153 | 0.84 | ALDH1A1 (0.63) | MAPTHPGDMAPK1HTTNPC1 | |
| SCHEMBL7697078 | 0.83 | HPGD (0.56) | MAPTHPGDNPC1RAB9ACASP3 | |
| SCHEMBL7693588 | 0.83 | KDM4E (0.65) | MAPTHPGDCYP2C19NPC1RAB9A | |
| SCHEMBL7700048 | 0.83 | NPC1 (0.50) | MAPTHPGDMAPK1HTTNPC1 | |
| SCHEMBL7701960 | 0.83 | DGAT1 (0.52) | MAPTMAPK1HTTCETPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |