Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700172 | 0.88 | ALDH1A1 (0.35) | TSHRKMT2AGAASMN1; SMN2CNR2 | |
| SCHEMBL7702817 | 0.88 | ALDH1A1 (0.37) | TSHRKMT2AGAAALDH1A1TP53 | |
| SCHEMBL7697790 | 0.87 | ALDH1A1 (0.35) | TSHRKMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL7699554 | 0.87 | CA2 (0.37) | TSHRKMT2AGAAALDH1A1CA12 | |
| SCHEMBL7385304 | 0.81 | MAPT (0.39) | TSHRKMT2AGAAALDH1A1TP53 | |
| SCHEMBL7702331 | 0.81 | ALDH1A1 (0.45) | TSHRKMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL7388616 | 0.81 | TSHR (0.45) | TSHRKMT2AGAASMN1; SMN2CNR2 | |
| SCHEMBL7386010 | 0.80 | TSHR (0.45) | TSHRKMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL7699846 | 0.80 | TSHR (0.46) | TSHRKMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL7696668 | 0.80 | CA12 (0.48) | TSHRGAALMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346527-B1 | 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |