Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 10/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | HTR2A | P28223 | 7/20 | 0.41 |
| ▸ | DRD3 | P35462 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696975 | 0.92 | SLC2A1 (0.49) | CCR2SLC2A1OPRM1OPRK1OPRL1 | |
| SCHEMBL7705374 | 0.90 | SLC2A1 (0.46) | CCR2SLC2A1DRD2HTR2ADRD3 | |
| SCHEMBL7702984 | 0.86 | CCR2 (0.40) | CCR2SLC2A1OPRM1OPRK1DRD2 | |
| SCHEMBL7702546 | 0.85 | SLC2A1 (0.52) | CCR2SLC2A1DRD2HTR2ADRD3 | |
| SCHEMBL7702484 | 0.84 | OPRM1 (0.49) | CCR2SLC2A1OPRM1OPRK1OPRL1 | |
| SCHEMBL7700232 | 0.84 | SLC2A1 (0.69) | CCR2SLC2A1 | |
| SCHEMBL7700045 | 0.83 | CCR2 (0.56) | CCR2SLC2A1DRD2HTR2ADRD3 | |
| SCHEMBL7694620 | 0.83 | CCR2 (0.56) | CCR2SLC2A1DRD2HTR2ADRD3 | |
| SCHEMBL7701921 | 0.83 | CCR2 (0.56) | CCR2SLC2A1DRD2HTR2ADRD3 | |
| SCHEMBL7699820 | 0.81 | CCR2 (0.58) | CCR2SLC2A1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079190-A1 | 3-SUBSTITUTED INDOLES AS CHEMOKINE ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-10 | — | — | WO | disclosed |