Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | HCK | P08631 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701087 | 0.89 | DYRK1A (0.57) | DYRK1ALRRK2RETPIK3CDPIK3CG | |
| SCHEMBL7699522 | 0.89 | LRRK2 (0.56) | DYRK1ALRRK2RETPIK3CDPIK3CB | |
| SCHEMBL7701080 | 0.80 | LRRK2 (0.56) | DYRK1ALRRK2RETPIK3CDPIK3CG | |
| SCHEMBL7695818 | 0.78 | KDR (0.45) | DYRK1ALRRK2RETPIK3CDPIK3CB | |
| SCHEMBL7697867 | 0.75 | DYRK1A (0.54) | DYRK1ALRRK2RETKDM4EALDH1A1 | |
| SCHEMBL7701231 | 0.74 | DYRK1A (0.55) | DYRK1ALRRK2RETKDM4EALDH1A1 | |
| SCHEMBL30582621 | 0.73 | DYRK1A (1.00) | DYRK1ALRRK2PIK3CDPIK3CBPIK3CG | |
| SCHEMBL26110102 | 0.73 | DYRK1A (1.00) | DYRK1ALRRK2PIK3CDPIK3CBPIK3CG | |
| SCHEMBL7700326 | 0.68 | LRRK2 (0.52) | DYRK1ALRRK2RETKDM4EALDH1A1 | |
| SCHEMBL29590003 | 0.67 | DYRK1A (0.63) | DYRK1ALRRK2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |