Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699522 | 0.90 | LRRK2 (0.56) | LRRK2DYRK1AABL1RETPIK3CD | |
| SCHEMBL7701087 | 0.88 | DYRK1A (0.57) | LRRK2DYRK1AFYNABL1RET | |
| SCHEMBL7701238 | 0.80 | DYRK1A (0.56) | LRRK2DYRK1AABL1RETPIK3CD | |
| SCHEMBL7701691 | 0.75 | KDR (0.49) | LRRK2FYNABL1RETPIK3CD | |
| SCHEMBL8991109 | 0.72 | KDM4E (0.59) | LRRK2DYRK1API4KBCDK5CDK5R1 | |
| SCHEMBL3869722 | 0.72 | LMNA (0.43) | KDM4E | |
| SCHEMBL7698547 | 0.68 | LRRK2 (0.56) | LRRK2DYRK1APIK3CDPIK3CAPIK3CG | |
| SCHEMBL7695818 | 0.68 | KDR (0.45) | LRRK2DYRK1AABL1RETPIK3CD | |
| SCHEMBL8991442 | 0.68 | LRRK2 (0.53) | LRRK2DYRK1APIK3CDEGFRSRC | |
| SCHEMBL13268766 | 0.68 | ADORA2A (0.65) | PIK3CDEGFRPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |