Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699518 | 0.88 | KDM4E (0.57) | DYRK1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL7697867 | 0.88 | DYRK1A (0.54) | DYRK1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL7696582 | 0.88 | DYRK1A (0.57) | DYRK1AKDM4ELRRK2ADORA2AADORA1 | |
| SCHEMBL7701233 | 0.87 | DYRK1A (0.51) | DYRK1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL7700915 | 0.84 | DYRK1A (0.50) | DYRK1ALRRK2ADORA2AADORA1 | |
| SCHEMBL7701581 | 0.82 | DYRK1A (0.55) | DYRK1AKDM4ELRRK2ADORA2AADORA1 | |
| SCHEMBL7700326 | 0.79 | LRRK2 (0.52) | DYRK1AKDM4EALDH1A1GLAGAA | |
| SCHEMBL7695781 | 0.79 | DYRK1A (0.56) | DYRK1AKDM4ELRRK2ADORA2AADORA1 | |
| SCHEMBL7699589 | 0.78 | DYRK1A (0.55) | DYRK1AKDM4ELRRK2ADORA2AADORA1 | |
| SCHEMBL7702669 | 0.77 | DYRK1A (0.57) | DYRK1AKDM4EGAALRRK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |