Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | SRC | P12931 | 6/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701013 | 0.88 | ADORA2A (0.53) | ADORA2ASRCLCKTEKADORA1 | |
| SCHEMBL7696370 | 0.88 | ADORA2A (0.51) | ADORA2ASRCLCKTEKADORA1 | |
| SCHEMBL7699497 | 0.82 | IGF1R (0.43) | ADORA2ASRCLCKTEKHTT | |
| SCHEMBL7699582 | 0.82 | LRRK2 (0.43) | ADORA2ASRCLCKTEKADORA1 | |
| SCHEMBL7701571 | 0.81 | ALDH1A1 (0.41) | ADORA2ASRCLCKTEKHTT | |
| SCHEMBL7701585 | 0.81 | ADRA1D (0.48) | ADORA2ASRCLCKTEKADORA1 | |
| SCHEMBL7701507 | 0.78 | ADORA2A (0.50) | ADORA2ASRCLCKTEKADORA1 | |
| SCHEMBL7697684 | 0.77 | ADRA1D (0.41) | ADORA2ASRCHTTNPC1GALR3 | |
| SCHEMBL7701973 | 0.77 | ADORA2A (0.54) | ADORA2ASRCLCKTEKADORA1 | |
| SCHEMBL7704461 | 0.76 | HTT (0.42) | SRCLCKTEKHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |