Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 6/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | ABL2 | P42684 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701013 | 0.93 | ADORA2A (0.53) | ADRA1DADORA2ASRCIGF1RLCK | |
| SCHEMBL7698006 | 0.89 | EIF2AK3 (0.41) | ADRA1DSRCADKCFD | |
| SCHEMBL7701218 | 0.85 | RET (0.52) | ADRA1DADORA2ASRCLCKTEK | |
| SCHEMBL7701506 | 0.81 | ADORA2A (0.53) | ADORA2ASRCIGF1RLCKTEK | |
| SCHEMBL7699602 | 0.78 | ABCC1 (0.48) | ADORA2ASRCIGF1RLCKTEK | |
| SCHEMBL7701571 | 0.77 | ALDH1A1 (0.41) | ADORA2ASRCIGF1RLCKTEK | |
| SCHEMBL7699582 | 0.76 | LRRK2 (0.43) | ADORA2ASRCIGF1RLCKTEK | |
| SCHEMBL7701507 | 0.76 | ADORA2A (0.50) | ADORA2ASRCIGF1RLCKTEK | |
| SCHEMBL7695714 | 0.75 | ADRA1D (0.51) | ADRA1DSRCADKEGFRABL1 | |
| SCHEMBL7700881 | 0.74 | CFD (0.45) | SRCADKEGFRABL1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |