Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693997 | 0.91 | ATM (0.47) | L3MBTL1MAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL7699727 | 0.89 | IKBKB (0.42) | L3MBTL1MAPTTP53MAPK1NPC1 | |
| SCHEMBL7693907 | 0.87 | MEN1 (0.51) | L3MBTL1MAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL7697060 | 0.87 | IKBKB (0.40) | L3MBTL1SMN1; SMN2LMNAHTTIKBKB | |
| SCHEMBL7697995 | 0.86 | IKBKB (0.40) | NPC1SMN1; SMN2LMNAIKBKBABL1 | |
| SCHEMBL7699558 | 0.86 | IKBKB (0.42) | L3MBTL1MAPTTP53SMN1; SMN2LMNA | |
| SCHEMBL7696382 | 0.85 | L3MBTL1 (0.58) | L3MBTL1MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL7699252 | 0.83 | IKBKB (0.39) | L3MBTL1MAPTTP53SMN1; SMN2IKBKB | |
| SCHEMBL7695157 | 0.82 | IKBKB (0.48) | MAPTTP53NPC1KMT2AIKBKB | |
| SCHEMBL7699968 | 0.82 | ATM (0.49) | L3MBTL1MAPTTP53MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |