Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699727 | 0.91 | IKBKB (0.42) | IKBKBLMNASMN1; SMN2HPGDNPC1 | |
| SCHEMBL7697060 | 0.88 | IKBKB (0.40) | IKBKBLMNASMN1; SMN2ABL1BCR | |
| SCHEMBL7699558 | 0.87 | IKBKB (0.42) | IKBKBLMNATHRBSMN1; SMN2HPGD | |
| SCHEMBL7700386 | 0.87 | RAB9A (0.42) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL7701523 | 0.86 | L3MBTL1 (0.49) | IKBKBLMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7699252 | 0.85 | IKBKB (0.39) | IKBKBSMN1; SMN2ABL1BCR | |
| SCHEMBL7693907 | 0.84 | MEN1 (0.51) | LMNASMN1; SMN2ALDH1A1KCNH2MCHR1 | |
| SCHEMBL7699803 | 0.83 | NPC1 (0.44) | LMNASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL7693997 | 0.82 | ATM (0.47) | LMNATHRBSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7695157 | 0.82 | IKBKB (0.48) | IKBKBHPGDNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |