Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 6/20 | 0.35 |
| ▸ | BCR | P11274 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697060 | 0.95 | IKBKB (0.40) | IKBKBABL1BCRSMN1; SMN2L3MBTL1 | |
| SCHEMBL7699727 | 0.88 | IKBKB (0.42) | IKBKBABL1BCRSMN1; SMN2L3MBTL1 | |
| SCHEMBL7699558 | 0.86 | IKBKB (0.42) | IKBKBABL1BCRSMN1; SMN2L3MBTL1 | |
| SCHEMBL7697995 | 0.85 | IKBKB (0.40) | IKBKBABL1BCRSMN1; SMN2 | |
| SCHEMBL7701523 | 0.83 | L3MBTL1 (0.49) | IKBKBABL1BCRSMN1; SMN2L3MBTL1 | |
| SCHEMBL7693907 | 0.81 | MEN1 (0.51) | SMN1; SMN2L3MBTL1TP53MAPTS1PR4 | |
| SCHEMBL7695157 | 0.81 | IKBKB (0.48) | IKBKBHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL7693997 | 0.80 | ATM (0.47) | SMN1; SMN2L3MBTL1TP53MAPT | |
| SCHEMBL7700386 | 0.80 | RAB9A (0.42) | SMN1; SMN2MAPT | |
| SCHEMBL7693804 | 0.78 | IKBKB (0.45) | IKBKBHDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |