Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | CCR2 | P41597 | 11/20 | 0.57 |
| ▸ | HTR1B | P28222 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR1E | P28566 | 1/20 | 0.57 |
| ▸ | HTR1F | P30939 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | CCR5 | P51681 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694620 | 0.96 | CCR2 (0.56) | SLC2A1CCR2HTR1BDRD2HTR1A | |
| SCHEMBL7700232 | 0.91 | SLC2A1 (0.69) | SLC2A1CCR2 | |
| SCHEMBL7703003 | 0.91 | CCR2 (0.62) | SLC2A1CCR2HTR1BDRD2HTR1A | |
| SCHEMBL7700045 | 0.90 | CCR2 (0.56) | SLC2A1CCR2HTR1BDRD2HTR1A | |
| SCHEMBL7702546 | 0.88 | SLC2A1 (0.52) | SLC2A1CCR2HTR1BDRD2HTR1A | |
| SCHEMBL7699820 | 0.85 | CCR2 (0.58) | SLC2A1CCR2DRD2HTR1AHTR2A | |
| SCHEMBL7702720 | 0.84 | CCR2 (0.61) | SLC2A1CCR2HTR1BDRD2HTR1A | |
| SCHEMBL7705374 | 0.83 | SLC2A1 (0.46) | SLC2A1CCR2HTR1BDRD2HTR1A | |
| SCHEMBL7695531 | 0.82 | CCR2 (0.52) | SLC2A1CCR2HTR1BDRD2HTR1A | |
| SCHEMBL7701921 | 0.82 | CCR2 (0.56) | SLC2A1CCR2HTR1BDRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079190-A1 | 3-SUBSTITUTED INDOLES AS CHEMOKINE ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-10 | — | — | WO | disclosed |