SCHEMBL7704690

SCHEMBL7704690

COC(=O)C(OC(=O)OCc1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
KMT2A Q03164 4/20 0.49
RECQL P46063 1/20 0.47
MEN1 O00255 2/20 0.47
CYP2C9 P11712 4/20 0.46
CYP2C19 P33261 4/20 0.46
CYP1A2 P05177 3/20 0.46
CYP3A4 P08684 3/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 2/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ATM Q13315 1/20 0.45
POLB P06746 1/20 0.44
CYP2D6 P10635 1/20 0.44
CTSL P07711 1/20 0.44
CTSS P25774 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11517372 0.87 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1CYP2C9CYP2C19
SCHEMBL7701655 0.85 KMT2A (0.60) ALDH1A1KMT2AMEN1CYP3A4TSHR
SCHEMBL9675264 0.84 KMT2A (0.55) ALDH1A1KMT2ARECQLMEN1CYP2C9
SCHEMBL22356129 0.83 KMT2A (0.50) ALDH1A1KMT2AMEN1CYP3A4TSHR
SCHEMBL22355962 0.83 KMT2A (0.50) ALDH1A1KMT2AMEN1CYP3A4TSHR
SCHEMBL1549936 0.82 ALDH1A1 (0.64) ALDH1A1KMT2AMAPK1LMNASMN1; SMN2
SCHEMBL13936261 0.81 ALDH1A1 (0.51) ALDH1A1KMT2AMEN1CYP2C9CYP2C19
SCHEMBL6643704 0.80 ALDH1A1 (0.53) ALDH1A1KMT2AMAPK1LMNASMN1; SMN2
SCHEMBL6644537 0.80 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1CYP2C9CYP2C19
SCHEMBL12928384 0.79 ALDH1A1 (0.49) ALDH1A1KMT2AMEN1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6469193-B1 THREE COMPONENT COUPLINGS OF ALIPHATIC ALCOHOLS, ALKYL HALIDES AND CARBON DIOXIDE IN THE PRESENCE OF CESIUM CARBONATE AND TETRABUTYLAMMONIUM IODIDE UNIVERSITY OF SOUTH FLORIDA 2002-10-22 US disclosed
WO-2000050376-A9 EFFICIENT SYNTHESIS OF ALKYL CARBONATES UNIV SOUTH FLORIDA (US) 2001-10-11 WO disclosed
WO-2000050376-A2 EFFICIENT SYNTHESIS OF ALKYL CARBONATES UNIVERSITY OF SOUTH FLORIDA (US) 2000-08-31 WO disclosed