SCHEMBL7102659

SCHEMBL7102659

FC(C(F)(F)F)C(F)(F)Oc1cc(Cl)ccc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
USP2 O75604 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
ALDH1A1 P00352 4/20 0.39
TSHR P16473 4/20 0.39
HSD17B10 Q99714 2/20 0.39
NOS2 P35228 2/20 0.36
TP53 P04637 2/20 0.35
HTT P42858 2/20 0.35
LMNA P02545 2/20 0.33
SLC6A4 P31645 2/20 0.33
HPGD P15428 1/20 0.33
RHEB Q15382 1/20 0.33
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29624830 1.00 RECQL (0.43) RECQLMEN1KMT2AUSP2MAPT
SCHEMBL7751907 0.78 ALDH1A1 (0.41) RECQLMEN1KMT2AUSP2MAPT
SCHEMBL28921417 0.77 NOS2 (0.36) MEN1KMT2AMAPTALDH1A1TSHR
SCHEMBL15561456 0.74 TP53 (0.38) ALDH1A1TSHRHSD17B10NOS2TP53
SCHEMBL7701776 0.74 MEN1 (0.43) RECQLMEN1KMT2AUSP2MAPT
SCHEMBL29408804 0.74 MEN1 (0.43) RECQLMEN1KMT2AUSP2MAPT
SCHEMBL10517770 0.72 TP53 (0.44) MAPTALDH1A1TSHRHSD17B10NOS2
SCHEMBL7751671 0.72 ALDH1A1 (0.46) RECQLMEN1KMT2AUSP2MAPT
SCHEMBL28351619 0.72 MEN1 (0.42) RECQLMEN1KMT2AUSP2MAPT
SCHEMBL10764482 0.72 RECQL (0.47) RECQLMEN1KMT2AUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115043733-A Continuous flow nitration synthesis method and micro-channel reactor thereof 南京理工大学 2022-09-13 CN claimed
CN-115043733-A Continuous flow nitration synthesis method and micro-channel reactor thereof 南京理工大学 2022-09-13 CN disclosed
CN-115043733-A Continuous flow nitration synthesis method and micro-channel reactor thereof 南京理工大学 2022-09-13 CN disclosed
CN-113144710-B A retrieve filter equipment for lufenuron reduction catalyst 浙江南郊化学有限公司 2022-04-29 CN disclosed
CN-113144710-A A retrieve filter equipment for lufenuron reduction catalyst 浙江南郊化学有限公司 2021-07-23 CN disclosed
EP-0975569-B1 PROCESS FOR THE HYDROXYLATION OF 1,4-DICHLOROBENZENE SYNGENTA PARTICIPATIONS AG (CH) 2003-09-03 EP disclosed
EP-0975569-A1 PROCESS FOR THE HYDROXYLATION OF 1,4-DICHLOROBENZENE Novartis AG (CH) 2000-02-02 EP disclosed
WO-1998047843-A1 PROCESS FOR THE HYDROXYLATION OF 1,4-DICHLOROBENZENE NOVARTIS AG (CH) 1998-10-29 WO disclosed