Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702473 | 0.88 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTPOLBMEN1 | |
| SCHEMBL7695046 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTPOLBMEN1 | |
| SCHEMBL7696896 | 0.84 | KMT2A (0.41) | ALDH1A1TSHRMAPTPOLBKMT2A | |
| SCHEMBL7701010 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPTPOLBMEN1 | |
| SCHEMBL7697504 | 0.81 | MAPT (0.38) | ALDH1A1TSHRMAPTPOLBMEN1 | |
| SCHEMBL7701850 | 0.80 | TP53 (0.40) | ALDH1A1TSHRMAPTPOLBMEN1 | |
| SCHEMBL7694566 | 0.79 | UBE2N (0.42) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL7700902 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL7694405 | 0.78 | S1PR1 (0.38) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL7701804 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |