Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699872 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL7697504 | 0.87 | MAPT (0.38) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL7700627 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL7701800 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL7696896 | 0.81 | KMT2A (0.41) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL7700867 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL7701804 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL7694366 | 0.73 | MAPT (0.44) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL7700070 | 0.73 | TP53 (0.49) | ALDH1A1KDM4EMAPTTSHRHTT | |
| SCHEMBL7696848 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |