Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699119 | 0.90 | KDM4E (0.50) | ACHEALDH1A1HTTKDM4EHPGD | |
| SCHEMBL7695082 | 0.87 | MAPT (0.50) | IKBKBALDH1A1KDM4EADRB2HPGD | |
| SCHEMBL7704986 | 0.82 | HSD17B2 (0.42) | IKBKBALDH1A1HTTKDM4EHPGD | |
| SCHEMBL7699894 | 0.81 | IKBKB (0.54) | IKBKBALDH1A1KDM4EADRB2HPGD | |
| SCHEMBL7698844 | 0.80 | KDM4E (0.57) | ALDH1A1HTTKDM4EHPGDKMT2A | |
| SCHEMBL7704952 | 0.80 | SMN1; SMN2 (0.44) | IKBKBALDH1A1HTTKDM4EADRB2 | |
| SCHEMBL7699146 | 0.79 | MAPT (0.57) | ALDH1A1HTTKDM4EHPGDKMT2A | |
| SCHEMBL7701519 | 0.78 | KDM4E (0.52) | ALDH1A1HTTKDM4EHPGDKMT2A | |
| SCHEMBL7701939 | 0.77 | HSP90AA1 (0.47) | ALDH1A1HTTKDM4EADRB2HPGD | |
| SCHEMBL7703225 | 0.77 | IKBKB (0.46) | IKBKBALDH1A1HTTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |