Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 5/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.42 |
| ▸ | IKBKB | O14920 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693804 | 0.91 | IKBKB (0.45) | HSD17B2HSD17B1IKBKBALDH1A1MAPT | |
| SCHEMBL7705474 | 0.89 | IKBKB (0.42) | IKBKBALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL7701939 | 0.86 | HSP90AA1 (0.47) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL7695157 | 0.84 | IKBKB (0.48) | IKBKBALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL7701807 | 0.82 | IKBKB (0.43) | IKBKBALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL7694123 | 0.79 | KDM4E (0.53) | IKBKBALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL7703225 | 0.79 | IKBKB (0.46) | IKBKBALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL7699627 | 0.78 | IKBKB (0.40) | IKBKBALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL7700674 | 0.78 | RAB9A (0.42) | ALDH1A1MAPTKDM4ECYP3A4CYP2C9 | |
| SCHEMBL7696153 | 0.77 | ALDH1A1 (0.47) | IKBKBALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |