Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 4/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023738 | 0.74 | MAPK10 (0.56) | IRAK4HTR1ADRD2HTR7DRD4 | |
| SCHEMBL4964716 | 0.66 | SORD (0.35) | IRAK4HTR1ADRD2HTR7DRD4 | |
| SCHEMBL4018709 | 0.66 | MAPK10 (0.65) | HTR1ADRD2HTR7DRD4DRD3 | |
| SCHEMBL4197293 | 0.63 | SORD (0.40) | IRAK4HTR1ADRD2HTR7DRD4 | |
| Acetonitrile SCHEMBL6828681 | 0.61 | SORD (0.38) | IRAK4HTR1ADRD2HTR7DRD4 | |
| SCHEMBL2885891 | 0.61 | MAPK10 (0.65) | HTR1ADRD2HTR7DRD4DRD3 | |
| SCHEMBL2886155 | 0.60 | MAPK10 (0.61) | HTR1ADRD2HTR7DRD4DRD3 | |
| SCHEMBL5640834 | 0.60 | IRAK4 (0.35) | IRAK4HTR1ADRD2HTR7DRD4 | |
| SCHEMBL2885492 | 0.59 | MAPK10 (0.59) | HTR1ADRD2HTR7DRD4DRD3 | |
| SCHEMBL5596130 | 0.59 | IRAK4 (0.44) | IRAK4HTR1ADRD2HTR7DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |