Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SORD | Q00796 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
| ▸ | HTR7 | P34969 | 5/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596399 | 0.87 | HTR1A (0.48) | IRAK4AURKAFLT4NPC1RAB9A | |
| SCHEMBL5596653 | 0.73 | SCD (0.42) | NPC1RAB9AALDH1A1TSHRLMNA | |
| SCHEMBL4949763 | 0.68 | MAPK8 (0.41) | IRAK4AURKAFLT4NPC1RAB9A | |
| SCHEMBL4023738 | 0.67 | MAPK10 (0.56) | IRAK4NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL219434 | 0.67 | NPC1 (0.67) | NPC1RAB9AALDH1A1TSHRHSD17B10 | |
| SCHEMBL29373464 | 0.67 | NPC1 (0.67) | NPC1RAB9AALDH1A1TSHRHSD17B10 | |
| SCHEMBL5596467 | 0.67 | NPC1 (0.48) | NPC1RAB9AALDH1A1TSHRHSD17B10 | |
| SCHEMBL5596753 | 0.67 | ILK (0.56) | NPC1RAB9AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL5564234 | 0.66 | SORD (0.43) | IRAK4NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL5596604 | 0.65 | ILK (0.52) | IRAK4RAB9ATSHRTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |