Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740811 | 0.83 | JAK3 (0.33) | JAK3 | |
| SCHEMBL2491805 | 0.78 | SMN1; SMN2 (0.40) | JAK3SMN1; SMN2CYP1A2 | |
| SCHEMBL27261811 | 0.75 | JAK3 (0.35) | JAK3SMN1; SMN2 | |
| SCHEMBL8529801 | 0.75 | JAK3 (0.35) | JAK3SMN1; SMN2 | |
| SCHEMBL8529798 | 0.75 | JAK3 (0.35) | JAK3SMN1; SMN2 | |
| SCHEMBL7422568 | 0.74 | HPGD (0.39) | JAK3ALDH1A1SMN1; SMN2 | |
| SCHEMBL3460085 | 0.72 | SIRT3 (0.37) | JAK3ALDH1A1LMNA | |
| SCHEMBL4638784 | 0.71 | JAK3 (0.35) | JAK3ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9738264 | 0.70 | — | — | |
| SCHEMBL5069987 | 0.69 | JAK3 (0.34) | JAK3ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6428624-B1 | MIXTURE OF REDUCING SUGAR AND BASE CATALYST; MIXTURE ENRICHED IN AT LEAST ONE AMINO ACID OF SERINE, THREONINE, VALINE, LEUCINE AND ISOLEUCINE | R. J. REYNOLDS TOBACCO CO. | 2002-08-06 | — | — | US | disclosed |
| US-20020074008-A1 | Method of providing flavorful and aromatic compounds | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2002-06-20 | — | — | US | disclosed |