Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27261811 | 1.00 | JAK3 (0.35) | JAK3KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8529798 | 1.00 | JAK3 (0.35) | JAK3KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2491805 | 0.75 | SMN1; SMN2 (0.40) | JAK3KDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL7702136 | 0.75 | JAK3 (0.37) | JAK3SMN1; SMN2 | |
| SCHEMBL7422568 | 0.71 | HPGD (0.39) | JAK3KDM4ESMN1; SMN2 | |
| SCHEMBL5069987 | 0.71 | JAK3 (0.34) | JAK3POLB | |
| SCHEMBL3460085 | 0.69 | SIRT3 (0.37) | JAK3KDM4EPOLB | |
| SCHEMBL4638784 | 0.68 | JAK3 (0.35) | JAK3KDM4ESMN1; SMN2POLB | |
| SCHEMBL11201451 | 0.67 | MAPKAPK2 (0.35) | JAK3KDM4EPOLB | |
| Methyl Alcohol SCHEMBL16458351 | 0.66 | JAK3 (0.42) | JAK3KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763640-A | OXIMINOMETHYLPHENYL DERIVATIVES | ZENECA LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0370629-B2 | Fungicides | ZENECA LTD (GB) | 1998-01-07 | — | — | EP | disclosed |
| US-5631253-A | FUNGICIDES, INSECTICIDES AND MITICIDES USING METHYLOXIME PHENYLPROPENOIC ACID | ZENECA LIMITED (GB) | 1997-05-20 | — | — | US | disclosed |
| US-5432197-A | Insecticidal, miticidal | ZENECA LIMITED (GB) | 1995-07-11 | — | — | US | disclosed |
| US-5371084-A | Insecticides and miticides | ZENECA LIMITED (GB) | 1994-12-06 | — | — | US | disclosed |
| CN-1024005-C | Fungicidal agents | ICI PLC (GB) | 1994-03-16 | — | — | CN | disclosed |
| EP-0506149-A2 | Fungicides | ZENECA LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| US-5055471-A | FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-08 | — | — | US | disclosed |
| CN-1042900-A | Mycocide | ICI PLC (GB) | 1990-06-13 | — | — | CN | disclosed |
| EP-0370629-A1 | Fungicides | ZENECA LIMITED (GB) | 1990-05-30 | — | — | EP | disclosed |