SCHEMBL770229

SCHEMBL770229

C=C(C)C(=O)OCCC(=O)NCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
TSHR P16473 5/20 0.50
FAAH O00519 1/20 0.41
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MCL1 Q07820 1/20 0.34
HPGD P15428 1/20 0.34
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.32
EPHX1 P07099 1/20 0.32
KMT2A Q03164 1/20 0.31
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10482143 0.89 TSHR (0.53) THRBTSHRFAAHHPGDL3MBTL1
SCHEMBL10060088 0.86 THRB (0.50) THRBTSHRFAAHALDH1A1POLB
SCHEMBL2612452 0.86 TSHR (0.62) THRBTSHRFAAHPOLBAPEX1
SCHEMBL4917590 0.85 THRB (0.47) THRBTSHRFAAHALDH1A1POLB
SCHEMBL2611997 0.85 FAAH (0.44) THRBTSHRFAAHMCL1HPGD
SCHEMBL8351897 0.83 TSHR (0.57) THRBTSHRFAAHHPGD
SCHEMBL12310164 0.81 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9421254 0.81 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL18656239 0.81 THRB (0.46) THRBTSHRFAAHALDH1A1MCL1
SCHEMBL16309307 0.79 THRB (0.48) THRBTSHRFAAHALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2436365-B1 Composite material comprising a monomer with a polyalicyclic structure element VOCO GMBH (DE) 2017-03-08 EP disclosed
EP-2436363-B1 Compound comprising a monomer with a polyalicyclic structure element for filling and/or sealing a root canal VOCO GMBH (DE) 2017-01-18 EP disclosed
US-20160213891-A1 Medical Dilation Element ZAMORE, ALAN 2016-07-28 US disclosed
US-9333278-B2 Medical dilation element Medtech Capital Ventures LLC (US) 2016-05-10 US disclosed
EP-2436366-B1 Composite material comprising a monomer with a polyalicyclic structure as sealing material VOCO GMBH (DE) 2015-07-29 EP disclosed
US-9079828-B2 Polymerizable compounds comprising a polyalicylic structure element VOCO GMBH (DE) 2015-07-14 US disclosed
US-9079828-B2 Polymerizable compounds comprising a polyalicylic structure element VOCO GMBH (DE) 2015-07-14 US disclosed
US-9023916-B2 Composite material comprising a monomer with a polyalicyclic structure element VOCO GMBH (DE) 2015-05-05 US disclosed
US-9023916-B2 Composite material comprising a monomer with a polyalicyclic structure element VOCO GMBH (DE) 2015-05-05 US disclosed
US-8979535-B2 Compositions for infiltration and/or sealing of hard tooth tissue and corresponding methods VOCO GMBH (DE) 2015-03-17 US disclosed
US-4316952-A Energy sensitive element having crosslinkable polyester MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-02-23 US disclosed
EP-0044840-A1 INFORMATION CARRYING DISCS. MINNESOTA MINING & MFG (US) 1982-02-03 EP disclosed
US-4309529-A GRAPHIC ARTS, PHOTORESISTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-01-05 US disclosed
US-4306954-A IRRADIATION CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-12-22 US disclosed
EP-0040002-A1 Water-dispersible energy curable heterocyclic group-containing polyesters MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-11-18 EP disclosed
US-4296158-A Information carrying discs MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-10-20 US disclosed
WO-1981002137-A1 INFORMATION CARRYING DISCS MINNESOTA MINING & MFG (US) 1981-08-06 WO disclosed
EP-0030968-A4 IRRADIATION OF POLYACRYLATE COMPOSITIONS IN AIR. MINNESOTA MINING & MFG (US) 1981-07-09 EP disclosed
EP-0030968-A1 IRRADIATION OF POLYACRYLATE COMPOSITIONS IN AIR. MINNESOTA MINING & MFG (US) 1981-07-01 EP disclosed
WO-1981000012-A1 IRRADIATION OF POLYACRYLATE COMPOSITIONS IN AIR MINNESOTA MINING & MFG (US) 1981-01-08 WO disclosed