Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770229 | 0.81 | THRB (0.52) | THRBTSHRKDM4EALDH1A1FAAH | |
| SCHEMBL12472336 | 0.79 | FAAH (0.60) | KDM4EALDH1A1FAAHPKMMAPK1 | |
| SCHEMBL2853009 | 0.77 | TSHR (0.42) | THRBTSHRALDH1A1FAAHRAB9A | |
| SCHEMBL27360291 | 0.75 | TSHR (0.41) | THRBTSHRALDH1A1FAAHLMNA | |
| SCHEMBL2612452 | 0.75 | TSHR (0.62) | THRBTSHRFAAHHPGD | |
| SCHEMBL10060088 | 0.75 | THRB (0.50) | THRBTSHRALDH1A1FAAHLMNA | |
| SCHEMBL11544171 | 0.74 | THRB (0.44) | THRBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL890339 | 0.74 | THRB (0.58) | THRBTSHRALDH1A1 | |
| SCHEMBL16573572 | 0.74 | THRB (0.43) | THRBTSHRKDM4EALDH1A1FAAH | |
| SCHEMBL28070042 | 0.73 | TSHR (0.50) | THRBTSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081450-A1 | POLYMER PARTICLES | MICROVENTION, INC. | 2017-03-23 | — | — | US | disclosed |