Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 7/20 | 0.49 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698245 | 0.84 | PRCP (0.57) | PRCPGID4RECQLGAAMAPT | |
| SCHEMBL7699907 | 0.75 | PRCP (0.66) | PRCPGID4RECQLGAAMAPT | |
| SCHEMBL7699909 | 0.75 | PRCP (0.66) | PRCPGID4RECQLGAAMAPT | |
| SCHEMBL3066069 | 0.72 | PRCP (0.66) | PRCPGID4RECQLGAA | |
| SCHEMBL7705935 | 0.72 | PRCP (0.66) | PRCPGID4RECQLGAA | |
| SCHEMBL7702915 | 0.72 | PRCP (0.57) | PRCPGID4RECQLGAAMAPT | |
| SCHEMBL7702912 | 0.72 | PRCP (0.57) | PRCPGID4RECQLGAAMAPT | |
| SCHEMBL7700053 | 0.72 | TRPM8 (0.35) | PRCPTRPV1 | |
| SCHEMBL7702891 | 0.70 | PRCP (0.52) | PRCPGID4RECQLGAAMAPT | |
| SCHEMBL7702893 | 0.70 | PRCP (0.52) | PRCPGID4RECQLGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901488-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| EP-0901488-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043277-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-11-20 | — | — | WO | disclosed |