Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700894 | 0.86 | KMT2A (0.41) | MAPTALDH1A1TSHRKMT2AL3MBTL1 | |
| SCHEMBL7694411 | 0.80 | C1R (0.38) | MAPTALDH1A1TSHRHPGD | |
| SCHEMBL7698770 | 0.78 | MAPT (0.61) | MAPTALDH1A1TSHRKMT2AGAA | |
| SCHEMBL7669323 | 0.78 | MAPT (0.81) | MAPTALDH1A1TSHRKMT2AGAA | |
| SCHEMBL7674814 | 0.77 | MAPT (0.70) | MAPTALDH1A1TSHRKMT2AGAA | |
| SCHEMBL7668097 | 0.76 | MAPT (0.74) | MAPTALDH1A1TSHRKMT2AGAA | |
| SCHEMBL7696680 | 0.75 | MAPT (0.62) | MAPTALDH1A1KMT2AGAATP53 | |
| SCHEMBL3024285 | 0.74 | MAPT (1.00) | MAPTALDH1A1TSHRKMT2AGAA | |
| SCHEMBL7670400 | 0.73 | MAPT (0.67) | MAPTALDH1A1TSHRKMT2AL3MBTL1 | |
| SCHEMBL7700596 | 0.72 | L3MBTL1 (0.53) | MAPTALDH1A1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |