Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | UTRN | P46939 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700894 | 0.82 | KMT2A (0.41) | C1RBCAT1HSD11B1LMNAPOLB | |
| SCHEMBL7701107 | 0.81 | C1R (0.46) | C1RPSMB8NOTUMALDH1A1TSHR | |
| SCHEMBL7702510 | 0.80 | MAPT (0.58) | ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL7700594 | 0.72 | C1R (0.44) | C1RPSMB8NOTUMALDH1A1TSHR | |
| SCHEMBL7699705 | 0.71 | C1R (0.43) | C1RPSMB8NOTUMALDH1A1TSHR | |
| SCHEMBL7702036 | 0.66 | MAPT (0.62) | ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL7663107 | 0.63 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTKDM4EHPGD | |
| SCHEMBL7700431 | 0.61 | TP53 (0.47) | LMNAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL7700596 | 0.61 | L3MBTL1 (0.53) | LMNAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL7701108 | 0.61 | KMT2A (0.62) | C1RLMNAALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |