Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702510 | 0.86 | MAPT (0.58) | KMT2AALDH1A1MAPTL3MBTL1TSHR | |
| SCHEMBL7694411 | 0.82 | C1R (0.38) | ALDH1A1MAPTLMNAKDM4EHSD11B1 | |
| SCHEMBL7701108 | 0.81 | KMT2A (0.62) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7700596 | 0.70 | L3MBTL1 (0.53) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7699708 | 0.68 | L3MBTL1 (0.56) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7700470 | 0.67 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7702037 | 0.66 | MEN1 (0.77) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7699365 | 0.65 | L3MBTL1 (0.75) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7698770 | 0.64 | MAPT (0.61) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL7696680 | 0.64 | MAPT (0.62) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |