Biphenyl

Biphenyl

SCHEMBL7702707

CC(C)(C)c1ccc(Br)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
MAPK1 P28482 1/20 0.61
KIF11 P52732 5/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
TSHR P16473 1/20 0.42
LMNA P02545 1/20 0.41
TYR P14679 1/20 0.41
MAPT P10636 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP19A1 P11511 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HSD17B2 P37059 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL2569681 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1KIF11SMN1; SMN2NPC1
Bromobenzene SCHEMBL9230161 0.91 ALDH1A1 (0.55) ALDH1A1MAPK1KIF11SMN1; SMN2NPC1
SCHEMBL177404 0.88 KIF11 (0.56) ALDH1A1MAPK1KIF11SMN1; SMN2NPC1
SCHEMBL12367606 0.88 KIF11 (0.56) ALDH1A1MAPK1KIF11SMN1; SMN2NPC1
SCHEMBL27959115 0.87 ALDH1A1 (0.52) ALDH1A1MAPK1KIF11SMN1; SMN2NPC1
SCHEMBL27959121 0.87 ALDH1A1 (0.52) ALDH1A1MAPK1KIF11SMN1; SMN2NPC1
SCHEMBL3421942 0.85 KIF11 (0.59) ALDH1A1KIF11NPC1RAB9ATSHR
SCHEMBL128222 0.85 KIF11 (0.59) ALDH1A1KIF11NPC1RAB9ATSHR
SCHEMBL5758 0.85 TSHR (0.55) ALDH1A1MAPK1KIF11SMN1; SMN2NPC1
SCHEMBL17948170 0.84 ALDH1A1 (0.71) ALDH1A1MAPK1KIF11SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed