SCHEMBL128222

SCHEMBL128222

CC(C)(C)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.59
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C9 P11712 1/20 0.48
LMNA P02545 1/20 0.48
TYR P14679 1/20 0.48
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
CYP19A1 P11511 2/20 0.46
HSD17B2 P37059 1/20 0.46
DHODH Q02127 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
TNF P01375 1/20 0.46
NOD1 Q9Y239 1/20 0.46
XDH P47989 1/20 0.45
PTPN5 P54829 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3421942 1.00 KIF11 (0.59) KIF11ALDH1A1TSHRCYP2C9LMNA
Ethane SCHEMBL27903947 0.97 KIF11 (0.57) KIF11ALDH1A1TSHRCYP2C9LMNA
SCHEMBL26771321 0.93 DHODH (0.54) KIF11ALDH1A1TSHRCYP2C9RXRA
SCHEMBL28102065 0.93 DHODH (0.54) KIF11ALDH1A1TSHRCYP2C9RXRA
SCHEMBL18801808 0.93 KIF11 (0.53) KIF11ALDH1A1TSHRCYP2C9LMNA
Biphenyl SCHEMBL27660679 0.92 ALDH1A1 (0.53) KIF11ALDH1A1TSHRLMNATYR
Tert-Butylbenzene SCHEMBL10970404 0.92 KIF11 (0.54) KIF11ALDH1A1TSHRLMNATYR
SCHEMBL22793707 0.91 DHODH (0.57) KIF11ALDH1A1RXRARXRBHSD17B2
P-Xylene SCHEMBL1419675 0.91 TSHR (0.68) KIF11ALDH1A1TSHRCYP2C9LMNA
Bicarbonate SCHEMBL27587346 0.91 CYP2C9 (0.57) KIF11CYP2C9LMNARXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724768-A N-alkyl substituted nitrogen-containing compound and preparation method thereof 武汉光化学技术研究院 2024-10-01 CN claimed
CN-118005471-A Novel method for synthesizing 4-tert-butyl biphenyl by using palladium to catalyze tetrafluorothianthrene salt 内蒙古大学 2024-05-10 CN claimed
CN-117603124-A Double-main-body organic electroluminescent material and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2024-02-27 CN claimed
CN-105153241-B Carbonylation ligands and their use in the carbonylation of ethylenically unsaturated compounds 卢西特国际英国有限公司 2020-05-15 CN claimed
EP-2490291-B1 LITHIUM SECONDARY BATTERY, AND NON-AQUEOUS ELECTROLYTIC SOLUTION FOR USE IN THE LITHIUM SECONDARY BATTERY UBE INDUSTRIES (JP) 2014-12-03 EP claimed
US-8377948-B2 Antitumor agents and methods of their use THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2013-02-19 US claimed
EP-2490291-A1 LITHIUM SECONDARY BATTERY, AND NON-AQUEOUS ELECTROLYTIC SOLUTION FOR USE IN THE LITHIUM SECONDARY BATTERY Ube Industries, Ltd. (JP) 2012-08-22 EP claimed
US-20120183846-A1 LITHIUM SECONDARY BATTERY, AND NON-AQUEOUS ELECTROLYTIC SOLUTION FOR USE IN THE LITHIUM SECONDARY BATTERY UBE INDUSTRIES, LTD. (JP) 2012-07-19 US claimed
EP-1691441-B1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME UBE INDUSTRIES (JP) 2012-03-07 EP claimed
US-7794885-B2 Non-aqueous electrolytic solution and lithium secondary battery UBE INDUSTRIES, LTD. (JP) 2010-09-14 US claimed
CN-101553496-A Novel carbonylation ligands and their use in the carbonylation of ethylenically unsaturated compounds LUCITE INT UK LTD (GB) 2009-10-07 CN claimed
US-20090048265-A1 NOVEL ANTITUMOR AGENTS AND METHODS OF THEIR USE THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2009-02-19 US claimed
US-20080248399-A1 Comprises an electrolyte salt in a non-aqueous solvent which contains a tert-alkylbenzene compound of high purity; battery improved in safety, excellent in cycle performance and storage performance at a high temperature, improved safety UBE INDUSTRIES, LTD. (JP) 2008-10-09 US claimed
EP-1361622-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERIES UBE INDUSTRIES (JP) 2008-06-04 EP claimed
US-20080050658-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERIES UBE INDUSTRIES, LTD. (JP) 2008-02-28 US claimed
US-20070082271-A1 Non-aqueous electrolytic solution and lithium secondary battery UBE INDUSTRIES, LTD. (JP) 2007-04-12 US claimed
EP-1691441-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY Ube Industries, Ltd. (JP) 2006-08-16 EP claimed
US-20040121239-A1 Nonaqueous electrolytic solution and lithium secondary batteries UBE INDUSTRIES, LTD. (JP) 2004-06-24 US claimed
EP-1361622-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERIES Ube Industries, Ltd. (JP) 2003-11-12 EP claimed
US-4271002-A Calcium ion-selective electrodes and membrane for use therein BECKMAN INSTRUMENTS, INC. (US) 1981-06-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048265-A1 NOVEL ANTITUMOR AGENTS AND METHODS OF THEIR USE ADRB1, ADRA2A, ADRA1A KIF11 2784/4885ALDH1A1 219/4885TSHR 2380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.